The AHI is an important metric that conveys information regarding the severity of sleep apnea, influences treatment decisions, and has prognostic implications. Currently there is no consensus regarding the appropriate definition of a hypopnea. Future studies are needed to examine the effect of various definitions used to calculate AHI in order to determine which definition correlates best with long-term outcomes (eg, cardiovascular, neurocognitive, psychiatric, metabolic) in different age, sex, and BMI subgroups.
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